Neutrinos are one of the most puzzling particle in the current Standard Model of Particle Physics. Even if they are the second most abundant known particle in the Universe, scientists have very few hints of their nature and their properties. DUNE is a next generation experiments that will address the precise measurement of this particles, exploiting Argon in either liquid and gas phase. In order to asses the potentiality of this technology and estimate the physics potential of DUNE, a rich campaign of prototyping is currently underway at CERN, in Switzerland. My thesis research is focused on exporting the information that can be learned from the prototypes to the full-scale experiment, assess its design and improve the data analysis techniques.