Pietro Salvatore CAROLLO

Molecular Bases of Mechanotranduction through Cadherins and Nesprins
Promotion :
Field of Study :
Research Unit : "Mechanotransduction: from cell surface to nucleus" team
Thesis Description :

The project aims at assessing whether Cadherin and Nesprin proteins are involved in a common mechanotrasduction pathway implying Catenin protein release. To do so, we would like to apply mechanical forces directly on Cadherins and Nesprins or perturb them by means of drugs and/or protein mutants.