Pietro Salvatore CAROLLO

Molecular Bases of Mechanotranduction through Cadherins and Nesprins
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Unité de recherche : "Mechanotransduction: from cell surface to nucleus" team
Description de la thèse :

The project aims at assessing whether Cadherin and Nesprin proteins are involved in a common mechanotrasduction pathway implying Catenin protein release. To do so, we would like to apply mechanical forces directly on Cadherins and Nesprins or perturb them by means of drugs and/or protein mutants.