Pietro Salvatore CAROLLO
Molecular Bases of Mechanotranduction through Cadherins and Nesprins
Etablissement : Université Paris Diderot
Promotion : 2016
Domaine d’étude : Sciences de la vie et de la santé
Unité de recherche : "Mechanotransduction: from cell surface to nucleus" team
Ecole doctorale :
Frontières du Vivant (FdV)
Description de la thèse :
The project aims at assessing whether Cadherin and Nesprin proteins are involved in a common mechanotrasduction pathway implying Catenin protein release. To do so, we would like to apply mechanical forces directly on Cadherins and Nesprins or perturb them by means of drugs and/or protein mutants.